CDC40 antibody (N-Term)

Catalog No. ABIN2789853

Product Details anti-CDC40 Antibody

Target: CDC40 (Cell Division Cycle 40 (CDC40))

Binding Specificity: N-Term

Reactivity: Mouse, Rat, Human, Cow, Dog, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC40 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NQGLTVFETG QKKTEKRKKF KENDASNIDG FLGPWAKYVD EKDVAKPSEE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against CDC40. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 579 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDC40

Target: CDC40 (Cell Division Cycle 40 (CDC40))

Alternative Name: CDC40 (CDC40 Products)

Background: Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression.
Alias Symbols: EHB3, FLJ10564, MGC102802, PRP17, PRPF17
Protein Interaction Partner: UBC, SUZ12, PRPF19, EIF4A3, MAGOH, DIABLO, RNF31, HTRA2, TRAF6, TRAF5, TRAF3, TRAF2, TRAF1, IKBKB, CHUK, CD40, BIRC2, Snw1, TADA2A, SMURF1, DHX38, SMAD2, Eps15l1, Eps15,
Protein Size: 579

Molecular Weight: 65 kDa

Gene ID: 51362

NCBI Accession: NM_015891, NP_056975

UniProt: O60508

Pathways: Ribonucleoprotein Complex Subunit Organization