GBE1 antibody (N-Term)

Catalog No. ABIN2789854

This anti-GBE1 antibody is a Rabbit Polyclonal antibody detecting GBE1 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for GBE1 antibody (N-Term) (ABIN2789854)

Target: GBE1 (Glucan (1,4-alpha-), Branching Enzyme 1 (GBE1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBE1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GBE1 Antibody

Binding Specificity: N-Term

Sequence: IHWDPEHSYE FKHSRPKKPR SLRIYESHVG ISSHEGKVAS YKHFTCNVLP

Predicted Reactivity: Cow: 83%, Dog: 83%, Guinea Pig: 85%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against GBE1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 702 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GBE1

Target: GBE1 (Glucan (1,4-alpha-), Branching Enzyme 1 (GBE1))

Alternative Name: GBE1

Background: The protein encoded by this gene is a glycogen branching enzyme that catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on the same or a neighboring glycogen chain. Branching of the chains is essential to increase the solubility of the glycogen molecule and, consequently, in reducing the osmotic pressure within cells. Highest level of this enzyme are found in liver and muscle. Mutations in this gene are associated with glycogen storage disease IV (also known as Andersen's disease).
Alias Symbols: GBE
Protein Interaction Partner: UBC, SUMO1, NEDD8, PRMT6, EPHB3, TRDMT1, DAK, UBD, ELAVL1, SUMO2, PGD,
Protein Size: 702

Molecular Weight: 80 kDa

Gene ID: 2632

NCBI Accession: NM_000158, NP_000149

UniProt: Q04446

Pathways: Cellular Glucan Metabolic Process