GPC4 antibody (C-Term)

Catalog No. ABIN2789855

This Rabbit Polyclonal antibody specifically detects GPC4 in WB. It exhibits reactivity toward Human, Mouse, Rat, Rabbit, Cow and Guinea Pig.It has been mentioned in 1 publication

Quick Overview for GPC4 antibody (C-Term) (ABIN2789855)

Target: GPC4 (Glypican 4 (GPC4))

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPC4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GPC4 Antibody

Binding Specificity: C-Term

Purpose: GPC4 Antibody - C-terminal region

Sequence: EYQQCPSEFD YNATDHAGKS ANEKADSAGV RPGAQAYLLT VFCILFLVMQ

Predicted Reactivity: Cow: 79%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against GPC4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human GPC4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64505-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-GPC4 antibody (ABIN2789855)

Walshe, Harkin: "Serial explant culture provides novel insights into the potential location and phenotype of corneal endothelial progenitor cells." in: Experimental eye research, Vol. 127, pp. 9-13, (2014) (PubMed).

Target Details for GPC4

Target: GPC4 (Glypican 4 (GPC4))

Alternative Name: GPC4

Background:

Background Information: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome.

Gene Name: glypican 4

Alternative Symbols: KPTS, K-glypican

Protein Name: glypican-4

Molecular Weight: 53kDa

Gene ID: 2239

NCBI Accession: NP_001439

UniProt: B4E2C0

Pathways: Glycosaminoglycan Metabolic Process