MAEA antibody (N-Term)

Catalog No. ABIN2789858

The Rabbit Polyclonal anti-MAEA antibody is suitable to detect MAEA in samples from Human, Rat, Mouse, Cow, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit and Dog. It has been validated for WB.

Quick Overview for MAEA antibody (N-Term) (ABIN2789858)

Target: MAEA (Macrophage erythroblast Attacher (MAEA))

Reactivity: Human, Rat, Mouse, Cow, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAEA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAEA Antibody

Binding Specificity: N-Term

Purpose: MAEA Antibody - N-terminal region

Sequence: RFRAAQKNID RETSHVTMVV AELEKTLSGC PAVDSVVSLL DGVVEKLSVL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against MAEA. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64512-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAEA

Target: MAEA (Macrophage erythroblast Attacher (MAEA))

Alternative Name: MAEA

Background:

Background Information: This gene product mediates the attachment of erythroblasts to macrophages. This attachment promotes terminal maturation and enucleation of erythroblasts, presumably by suppressing apoptosis. This protein is an integral membrane protein with the N-terminus on the extracellular side and the C-terminus on the cytoplasmic side of the cell. Two immunologically related isoforms of erythroblast macrophage protein with apparent molecular weights of 33 kD and 36 kD were detected in macrophage membranes, this gene encodes the larger isoform. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.

Gene Name: Macrophage erythroblast attacher

Alternative Symbols: EMP, EMLP, GID9, PIG5, HLC-10, P44EMLP

Protein Name: Macrophage erythroblast attacher

Molecular Weight: 40kDa

Gene ID: 10296

NCBI Accession: NP_005873

UniProt: Q7L5Y9