NCK1 antibody (N-Term)
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- Target See all NCK1 Antibodies
- NCK1 (NCK Adaptor Protein 1 (NCK1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NCK1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- PSNYVERKNS ARKASIVKNL KDTLGIGKVK RKPSVPDSAS PADDSFVDPG
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against NCK1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product NCK1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 377 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- NCK1 (NCK Adaptor Protein 1 (NCK1))
- Alternative Name
- NCK1 (NCK1 Products)
- Synonyms
- NCK antibody, NCKalpha antibody, nck-1 antibody, NCK1 antibody, 6330586M15Rik antibody, D230010O13Rik antibody, Nck antibody, Nck-1 antibody, Nck1 antibody, nck antibody, nck1-a antibody, nck1-b antibody, nckalpha antibody, NCK adaptor protein 1 antibody, non-catalytic region of tyrosine kinase adaptor protein 1 antibody, NCK adaptor protein 1b antibody, NCK adaptor protein 1 L homeolog antibody, NCK1 antibody, Nck1 antibody, nck1b antibody, nck1.L antibody
- Background
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The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.
Alias Symbols: MGC12668, NCK, NCKalpha, nck-1
Protein Interaction Partner: UBC, CBL, SYNPO, WAS, Dok1, HSPA5, Mbp, SHANK3, KIAA1522, Caskin1, LPHN2, ADAM15, TUBA1A, ERBB3, EGFR, PHC2, FGFR1, MAP4K1, BCAR1, nef, ABI1, PAK1, DNM1, ABL1, TNK2, FASLG, UBASH3B, SYK, PIK3R1, LCP2, INPP5D, GRB2, KHDRBS1, UBA52, RASA1, NCKAP5, TNIK, BRK
Protein Size: 377 - Molecular Weight
- 42 kDa
- Gene ID
- 4690
- NCBI Accession
- NM_006153, NP_006144
- UniProt
- P16333
- Pathways
- TCR Signaling, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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