USO1 antibody (C-Term)

Catalog No. ABIN2789890

This Rabbit Polyclonal antibody specifically detects USO1 in WB. It exhibits reactivity toward Human, Rat, Dog, Horse and Pig.

Quick Overview for USO1 antibody (C-Term) (ABIN2789890)

Target: USO1 (USO1 Homolog, Vesicle Docking Protein (USO1))

Reactivity: Human, Rat, Dog, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USO1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-USO1 Antibody

Binding Specificity: C-Term

Sequence: QNEQLQTAVT QQVSQIQQHK DQYNLLKIQL GKDNQHQGSY SEGAQMNGIQ

Predicted Reactivity: Dog: 92%, Horse: 79%, Human: 100%, Pig: 77%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against USO1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 962 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for USO1

Target: USO1 (USO1 Homolog, Vesicle Docking Protein (USO1))

Alternative Name: USO1

Background: The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner.
Alias Symbols: P115, TAP, VDP
Protein Interaction Partner: PHYKPL, XPO7, DUSP12, AKAP9, HUWE1, USO1, SUMO2, UBC, UBD, PDE4DIP, TRIP11, TRAF3, PRKAR2B, PRKACA, GOLGA2, SEC16A, CCDC168, FAM184A, CEP68, USP28, ZNF593, VCL, XIAP, MAPK3, TP53, NCOA2, BET1L, YKT6, GABPB1, C1orf94, EEA1, GOSR2, GOSR1, GBF1, STX5, STXBP1
Protein Size: 962

Molecular Weight: 108 kDa

Gene ID: 8615

NCBI Accession: NM_003715, NP_003706

UniProt: O60763