USO1 antibody (N-Term)

Catalog No. ABIN2789891

The Rabbit Polyclonal anti-USO1 antibody has been validated for WB. It is suitable to detect USO1 in samples from Human, Mouse, Rat, Dog, Horse, Pig, Cow, Guinea Pig and Rabbit.

Quick Overview for USO1 antibody (N-Term) (ABIN2789891)

Target: USO1 (USO1 Homolog, Vesicle Docking Protein (USO1))

Reactivity: Human, Mouse, Rat, Dog, Horse, Pig, Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USO1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-USO1 Antibody

Binding Specificity: N-Term

Sequence: QTDRSDSEII GYALDILYNI ISNEEEEEVE ENSTRQSEDL GSQFTEIFIK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against USO1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human USO1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 962 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for USO1

Target: USO1 (USO1 Homolog, Vesicle Docking Protein (USO1))

Alternative Name: USO1

Background: The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner.
Alias Symbols: P115, TAP, VDP
Protein Interaction Partner: PHYKPL, XPO7, DUSP12, AKAP9, HUWE1, USO1, SUMO2, UBC, UBD, PDE4DIP, TRIP11, TRAF3, PRKAR2B, PRKACA, GOLGA2, SEC16A, CCDC168, FAM184A, CEP68, USP28, ZNF593, VCL, XIAP, MAPK3, TP53, NCOA2, BET1L, YKT6, GABPB1, C1orf94, EEA1, GOSR2, GOSR1, GBF1, STX5, STXBP1
Protein Size: 962

Molecular Weight: 108 kDa

Gene ID: 8615

NCBI Accession: NM_003715, NP_003706

UniProt: O60763