GPS2 antibody (N-Term)

Catalog No. ABIN2789898

This Rabbit Polyclonal antibody specifically detects GPS2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae and Zebrafish (Danio rerio).

Quick Overview for GPS2 antibody (N-Term) (ABIN2789898)

Target: GPS2 (G Protein Pathway Suppressor 2 (GPS2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GPS2 Antibody

Binding Specificity: N-Term

Sequence: LKKVLHEEEK RRRKEQSDLT TLTSAAYQQS LTVHTGTHLL NMQGSPGGHN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against Gps2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of mouse GPS2

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GPS2

Target: GPS2 (G Protein Pathway Suppressor 2 (GPS2))

Alternative Name: Gps2

Background: This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.
Alias Symbols: AMF-1
Protein Size: 327

Molecular Weight: 37 kDa

Gene ID: 2874

NCBI Accession: NM_004489, NP_004480

UniProt: Q13227