GPS2 antibody (AA 30-110)

Catalog No. ABIN7221282

The Rabbit Polyclonal anti-GPS2 antibody (ABIN7221282) specifically detects GPS2 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GPS2 antibody (AA 30-110) (ABIN7221282)

Target: GPS2 (G Protein Pathway Suppressor 2 (GPS2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPS2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GPS2 Antibody

Binding Specificity: AA 30-110

Purpose: Rabbit Anti-GPS2 Polyclonal Antibody

Specificity: GPS2 Polyclonal Antibody detects endogenous levels of GPS2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human GPS2 at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GPS2

Target: GPS2 (G Protein Pathway Suppressor 2 (GPS2))

Alternative Name: GPS2

Background: GPS2, G protein pathway suppressor 2, GPS-2GPS2 encodes G protein pathway suppressor 2 involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.

Molecular Weight: 40kD

Gene ID: 2874

UniProt: Q13227