HRH1 antibody (Middle Region)

Catalog No. ABIN2789899

The Rabbit Polyclonal anti-HRH1 antibody is suitable to detect HRH1 in samples from Human, Dog, Pig and Rabbit. It has been validated for WB.

Quick Overview for HRH1 antibody (Middle Region) (ABIN2789899)

Target: HRH1 (Histamine Receptor H1 (HRH1))

Reactivity: Human, Dog, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HRH1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HRH1 Antibody

Binding Specificity: Middle Region

Purpose: HRH1 Antibody - middle region

Sequence: ENPKGDAKKP GKESPWEVLK RKPKDAGGGS VLKSPSQTPK EMKSPVVFSQ

Predicted Reactivity: Dog: 86%, Human: 100%, Pig: 79%, Rabbit: 79%

Characteristics: This is a rabbit polyclonal antibody against HRH1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64612-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HRH1

Target: HRH1 (Histamine Receptor H1 (HRH1))

Alternative Name: HRH1

Background:

Background Information: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene Name: Histamine receptor H1

Alternative Symbols: H1R, H1-R, HH1R, hisH1

Protein Name: Histamine H1 receptor

Molecular Weight: 56kDa

Gene ID: 3269

NCBI Accession: NP_000852

UniProt: P35367

Pathways: Regulation of Carbohydrate Metabolic Process