FCAR antibody (C-Term)

Catalog No. ABIN2789926

The Rabbit Polyclonal anti-FCAR antibody is suitable to detect FCAR in samples from Human. It has been validated for WB.

Quick Overview for FCAR antibody (C-Term) (ABIN2789926)

Target: FCAR (Fc Fragment of IgA, Receptor For (FCAR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FCAR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FCAR Antibody

Binding Specificity: C-Term

Purpose: FCAR Antibody - C-terminal region

Sequence: FDRFSLAKEG ELSLPQHQSG EHPANFSLGP VDLNVSGIYR LHPPRLHDAE

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against FCAR. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64692-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for FCAR

Target: FCAR (Fc Fragment of IgA, Receptor For (FCAR))

Alternative Name: FCAR

Background:

Background Information: This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Name: Fc fragment of IgA, receptor for

Alternative Symbols: CD89, FcalphaRI, CTB-61M7.2

Protein Name: Immunoglobulin alpha Fc receptor

Molecular Weight: 23kDa

Gene ID: 2204

NCBI Accession: NP_579808

UniProt: Q92588