HBG2 antibody (Middle Region)

Catalog No. ABIN2789939

The Rabbit Polyclonal anti-HBG2 antibody (ABIN2789939) specifically detects HBG2 in WB. The antibody is reactive with Human, Mouse, Cow, Dog, Goat, Guinea Pig, Horse, Pig, Rabbit, Rat and Sheep samples.

Quick Overview for HBG2 antibody (Middle Region) (ABIN2789939)

Target: HBG2 (Hemoglobin, gamma G (HBG2))

Reactivity: Human, Mouse, Cow, Dog, Goat, Guinea Pig, Horse, Pig, Rabbit, Rat, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HBG2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HBG2 Antibody

Binding Specificity: Middle Region

Purpose: HBG2 Antibody - middle region

Sequence: MGNPKVKAHG KKVLTSLGDA IKHLDDLKGT FAQLSELHCD KLHVDPENFK

Predicted Reactivity: Cow: 100%, Dog: 77%, Goat: 100%, Guinea Pig: 77%, Horse: 77%, Human: 100%, Mouse: 83%, Pig: 93%, Rabbit: 75%, Rat: 83%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against HBG2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64733-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HBG2

Target: HBG2 (Hemoglobin, gamma G (HBG2))

Alternative Name: HBG2

Background:

Targeted Subunit: gamma-2

Background Information: The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Gene Name: Hemoglobin, gamma G

Alternative Symbols: TNCY, HBG-T1

Protein Name: Hemoglobin subunit gamma-2

Molecular Weight: 16kDa

Gene ID: 3048

NCBI Accession: NP_000175

UniProt: P69892