BFSP2 antibody (Middle Region)

Catalog No. ABIN2789992

This Rabbit Polyclonal antibody specifically detects BFSP2 in WB. It exhibits reactivity toward Human, Mouse, Cow, Rat, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for BFSP2 antibody (Middle Region) (ABIN2789992)

Target: BFSP2 (Beaded Filament Structural Protein 2, Phakinin (BFSP2))

Reactivity: Human, Mouse, Cow, Rat, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BFSP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BFSP2 Antibody

Binding Specificity: Middle Region

Purpose: BFSP2 Antibody - middle region

Sequence: CQQVGEAVLE NARLMLQTET IQAGADDFKE RYENEQPFRK AAEEEINSLY

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against BFSP2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human BFSP2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64902-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for BFSP2

Target: BFSP2 (Beaded Filament Structural Protein 2, Phakinin (BFSP2))

Alternative Name: BFSP2

Background:

Background Information: More than 99 % of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (phakinin), and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex.

Gene Name: Beaded filament structural protein 2, phakinin

Alternative Symbols: CP47, CP49, LIFL-L, CTRCT12, PHAKOSIN

Protein Name: Phakinin

Molecular Weight: 46kDa

Gene ID: 8419

NCBI Accession: NP_003562

UniProt: Q13515