EI24 antibody (N-Term)

Catalog No. ABIN2790002

The Rabbit Polyclonal anti-EI24 antibody is suitable to detect EI24 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for EI24 antibody (N-Term) (ABIN2790002)

Target: EI24 (Etoposide Induced 2.4 (EI24))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EI24 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EI24 Antibody

Binding Specificity: N-Term

Purpose: EI24 Antibody - N-terminal region

Sequence: ICTISKLDAR IQQKREEQRR RRASSVLAQR RAQSIERKQE SEPRIVSRIF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 77%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against EI24. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64952-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for EI24

Target: EI24 (Etoposide Induced 2.4 (EI24))

Alternative Name: EI24

Background:

Background Information: This gene has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The protein encoded by this gene contains six putative transmembrane domains and may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in two transcript variants encoding different isoforms.

Gene Name: Etoposide induced 2.4 mRNA

Alternative Symbols: EPG4, PIG8, TP53I8

Protein Name: Etoposide-induced protein 2.4 homolog

Molecular Weight: 30kDa

Gene ID: 9538

NCBI Accession: NP_001007278

UniProt: O14681