KRT4 antibody (N-Term)

Catalog No. ABIN2790009

The Rabbit Polyclonal anti-KRT4 antibody (ABIN2790009) specifically detects KRT4 in WB. The antibody is reactive with Human, Rat, Mouse, Cow, Dog, Rabbit, Horse, Pig and Sheep samples.

Quick Overview for KRT4 antibody (N-Term) (ABIN2790009)

Target: KRT4 (Keratin 4 (KRT4))

Reactivity: Human, Rat, Mouse, Cow, Dog, Rabbit, Horse, Pig, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KRT4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KRT4 Antibody

Binding Specificity: N-Term

Purpose: KRT4 Antibody - N-terminal region

Sequence: SGKGGPGFPV CPAGGIQEVT INQSLLTPLH VEIDPEIQKV RTEEREQIKL

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 100%, Rat: 100%, Sheep: 86%

Characteristics: This is a rabbit polyclonal antibody against KRT4. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64964-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for KRT4

Target: KRT4 (Keratin 4 (KRT4))

Alternative Name: KRT4

Background:

Background Information: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Gene Name: Keratin 4

Alternative Symbols: K4, CK4, CK-4, CYK4, WSN1

Protein Name: Keratin, type II cytoskeletal 4

Molecular Weight: 56kDa

Gene ID: 3851

NCBI Accession: NP_002263

UniProt: F8VS64