Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CRYGA antibody (N-Term)

CRYGA Reactivity: Human, Cow, Dog, Guinea Pig, Horse, Mouse, Rabbit, Rat, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2790019
  • Target See all CRYGA products
    CRYGA (Crystallin, gamma A (CRYGA))
    Binding Specificity
    N-Term
    Reactivity
    Human, Cow, Dog, Guinea Pig, Horse, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
    Host
    • 1
    Rabbit
    Clonality
    • 1
    Polyclonal
    Conjugate
    • 1
    This CRYGA antibody is un-conjugated
    Application
    Western Blotting (WB)
    Sequence
    SIRVDSGCWM LYERPNYQGH QYFLRRGKYP DYQHWMGLSD SVQSCRIIPH
    Predicted Reactivity
    Cow: 79%, Dog: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 79%, Zebrafish: 82%
    Characteristics
    This is a rabbit polyclonal antibody against CRYGA. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human CRYGA
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 174 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CRYGA (Crystallin, gamma A (CRYGA))
    Alternative Name
    CRYGA (CRYGA Products)
    Synonyms
    CRY-g-A antibody, CRYG1 antibody, CRYG5 antibody, Cryg-4 antibody, DGcry-4 antibody, cryg1 antibody, cryg5 antibody, MGC85425 antibody, CRYGA antibody, crystallin gamma A antibody, crystallin, gamma A antibody, crystallin gamma A L homeolog antibody, gamma-crystallin A antibody, CRYGA antibody, Cryga antibody, cryga.L antibody, LOC100630282 antibody, LOC100355936 antibody
    Background
    Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.
    Alias Symbols: CRY-g-A, CRYG1, CRYG5
    Protein Interaction Partner: TRAF1,
    Protein Size: 174
    Molecular Weight
    21 kDa
    Gene ID
    1418
    NCBI Accession
    NM_014617, NP_055432
    UniProt
    P11844
You are here:
Support