BDKRB1 antibody (C-Term)

Catalog No. ABIN2790059

The Rabbit Polyclonal anti-BDKRB1 antibody is suitable to detect BDKRB1 in samples from Human and Rabbit. It has been validated for WB.

Quick Overview for BDKRB1 antibody (C-Term) (ABIN2790059)

Target: BDKRB1 (Bradykinin Receptor B1 (BDKRB1))

Reactivity: Human, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BDKRB1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BDKRB1 Antibody

Binding Specificity: C-Term

Purpose: BDKRB1 Antibody - C-terminal region

Sequence: NFFAFTNSSL NPVIYVFVGR LFRTKVWELY KQCTPKSLAP ISSSHRKEIF

Predicted Reactivity: Human: 100%, Rabbit: 77%

Characteristics: This is a rabbit polyclonal antibody against BDKRB1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65156-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for BDKRB1

Target: BDKRB1 (Bradykinin Receptor B1 (BDKRB1))

Alternative Name: BDKRB1

Background:

Background Information: Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene.

Gene Name: Bradykinin receptor B1

Alternative Symbols: B1R, BKR1, B1BKR, BKB1R, BRADYB1

Protein Name: B1 bradykinin receptor

Molecular Weight: 40kDa

Gene ID: 623

NCBI Accession: NP_000701

UniProt: P46663

Pathways: ACE Inhibitor Pathway