CDNF antibody (N-Term)

Catalog No. ABIN2790078

The Rabbit Polyclonal anti-CDNF antibody (ABIN2790078) specifically detects CDNF in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit and Zebrafish (Danio rerio) samples.

Quick Overview for CDNF antibody (N-Term) (ABIN2790078)

Target: CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDNF antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CDNF Antibody

Binding Specificity: N-Term

Purpose: CDNF Antibody - N-terminal region

Sequence: IDRGVNFSLD TIEKELISFC LDTKGKENRL CYYLGATKDA ATKILSEVTR

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against CDNF. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CDNF

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65224-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDNF

Target: CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))

Alternative Name: CDNF

Background:

Background Information: CDNF is a trophic factor for dopamine neurons. CDNF prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, CDNF restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra.

Alternative Symbols: ARMETL1

Protein Name: Cerebral dopamine neurotrophic factor

Molecular Weight: 21kDa

Gene ID: 441549

NCBI Accession: NP_001025125

UniProt: Q49AH0