DEF6 antibody (C-Term)

Catalog No. ABIN2790081

This Rabbit Polyclonal antibody specifically detects DEF6 in WB. It exhibits reactivity toward Human, Rat, Dog, Pig, Cow, Guinea Pig, Horse and Rabbit.

Quick Overview for DEF6 antibody (C-Term) (ABIN2790081)

Target: DEF6 (Differentially Expressed in FDCP 6 Homolog (DEF6))

Reactivity: Human, Rat, Dog, Pig, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEF6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DEF6 Antibody

Binding Specificity: C-Term

Sequence: SSSFSGFQPP LLAHRDSSLK RLTRWGSQGN RTPSPNSNEQ QKSLNGGDEA

Predicted Reactivity: Cow: 79%, Dog: 86%, Guinea Pig: 83%, Horse: 79%, Human: 100%, Pig: 86%, Rabbit: 79%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against DEF6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DEF6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 631 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DEF6

Target: DEF6 (Differentially Expressed in FDCP 6 Homolog (DEF6))

Alternative Name: DEF6

Background: DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC and CDC42 that is highly expressed in B and T cells.
Alias Symbols: IBP, SLAT, SWAP70L
Protein Interaction Partner: HOMEZ, PBXIP1, EIF4ENIF1, CDC42EP1, TCF4, PTK2, PLSCR1, UBC, APP, BEGAIN, RAC2, RAC1, ZAP70, RHOA, LCK, CDC42,
Protein Size: 631

Molecular Weight: 74 kDa

Gene ID: 50619

NCBI Accession: NM_022047, NP_071330

UniProt: Q9H4E7