DEF6 antibody (AA 51-100)

Catalog No. ABIN7228182

The Rabbit Polyclonal anti-DEF6 antibody (ABIN7228182) specifically detects DEF6 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for DEF6 antibody (AA 51-100) (ABIN7228182)

Target: DEF6 (Differentially Expressed in FDCP 6 Homolog (DEF6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEF6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DEF6 Antibody

Binding Specificity: AA 51-100

Purpose: Rabbit Anti-DEF6 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of DEF6 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human DEF6 protein at AA range: 51-100

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DEF6

Target: DEF6 (Differentially Expressed in FDCP 6 Homolog (DEF6))

Alternative Name: DEF6

Background: Defensin-6, Defensin, alpha 6Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by DEFA6, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of the small intestine, and likely plays a role in host defense of human bowel.

Molecular Weight: 11kD

Gene ID: 1671

UniProt: Q01524