Retinoic Acid Early Transcript 1E (RAET1E) (C-Term) antibody

Catalog No. ABIN1544462

The Rabbit Polyclonal anti-Retinoic Acid Early Transcript 1E antibody is suitable to detect Retinoic Acid Early Transcript 1E in samples from Human. It has been validated for WB.

Quick Overview for Retinoic Acid Early Transcript 1E (RAET1E) (C-Term) antibody (ABIN1544462)

Target: Retinoic Acid Early Transcript 1E (RAET1E)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: C-Term

Purpose: RAET1E Antibody - C-terminal region

Sequence: LEKYFRKLSK GDCDHWLREF LGHWEAMPEP TVSPVNASDI HWSSSSLPDR

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against RAET1E. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human RAET1E

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65271-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: Retinoic Acid Early Transcript 1E (RAET1E)

Alternative Name: RAET1E

Background:

Background Information: This gene belong to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. This and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative Symbols: RL-4, LETAL, ULBP4, N2DL-4, NKG2DL4, RAET1E2, bA350J20.7

Protein Name: NKG2D ligand 4

Molecular Weight: 27kDa

Gene ID: 135250

NCBI Accession: NP_631904

UniProt: Q8TD07