WNK2 antibody (N-Term)

Catalog No. ABIN2790096

This anti-WNK2 antibody is a Rabbit Polyclonal antibody detecting WNK2 in WB. Suitable for Human, Mouse, Rat, Dog, Guinea Pig and Horse.

Quick Overview for WNK2 antibody (N-Term) (ABIN2790096)

Target: WNK2 (WNK Lysine Deficient Protein Kinase 2 (WNK2))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WNK2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-WNK2 Antibody

Binding Specificity: N-Term

Sequence: APAPDGGPRE EAAATVRKED EGAAEAKPEP GRTRRDEPEE EEDDEDDLKA

Predicted Reactivity: Dog: 79%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against WNK2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human WNK2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 2217 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for WNK2

Target: WNK2 (WNK Lysine Deficient Protein Kinase 2 (WNK2))

Alternative Name: WNK2

Background: The protein encoded by this gene is a cytoplasmic serine-threonine kinase that contains cysteine in place of the lysine found at the conserved ATP-binding location in subdomain II of protein kinases. Since this protein does have kinase activity, it is possible that another lysine in the kinase subdomain I can substitute for the missing conserved lysine.
Alias Symbols: KIAA1760, NY-CO-43, P/OKcl.13, PRKWNK2, SDCCAG43
Protein Interaction Partner: KLHL3, KLHL2, DGCR14, ATXN1, SGK1, WNK1, YWHAZ,
Protein Size: 2217

Molecular Weight: 234 kDa

Gene ID: 65268

NCBI Accession: NM_006648, NP_006639

UniProt: F8W9F9

Pathways: Photoperiodism