WNK2 antibody (AA 1120-1200)

Catalog No. ABIN7232148

The Rabbit Polyclonal anti-WNK2 antibody is suitable to detect WNK2 in samples from Human and Mouse. It has been validated for IHC and IF.

Quick Overview for WNK2 antibody (AA 1120-1200) (ABIN7232148)

Target: WNK2 (WNK Lysine Deficient Protein Kinase 2 (WNK2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WNK2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-WNK2 Antibody

Binding Specificity: AA 1120-1200

Purpose: Rabbit Anti-WNK2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of WNK2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human WNK2 protein at AA range: 1120-1200

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for WNK2

Target: WNK2 (WNK Lysine Deficient Protein Kinase 2 (WNK2))

Alternative Name: WNK2

Background: Serine/threonine-protein kinase WNK2, Antigen NY-CO-43, Protein kinase lysine-deficient 2, Protein kinase with no lysine 2, Serologically defined colon cancer antigen 43WNK2 (WNK Lysine Deficient Protein Kinase 2) is a Protein Coding gene. Diseases associated with WNK2 include Gastric Cardia Carcinoma. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Ion channel transport. The protein encoded by WNK2 is a cytoplasmic serine-threonine kinase that belongs to the protein kinase superfamily. The protein plays an important role in the regulation of electrolyte homeostasis, cell signaling survival, and proliferation. Alternative splicing results in multiple transcript variants.

Molecular Weight: 252kD

Gene ID: 65268

UniProt: Q9Y3S1

Pathways: Photoperiodism