HCRTR1 antibody (N-Term)

Catalog No. ABIN2790108

This Rabbit Polyclonal antibody specifically detects HCRTR1 in WB. It exhibits reactivity toward Human, Rat, Rabbit, Dog, Cow and Guinea Pig.

Quick Overview for HCRTR1 antibody (N-Term) (ABIN2790108)

Target: HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))

Reactivity: Human, Rat, Rabbit, Dog, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HCRTR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HCRTR1 Antibody

Binding Specificity: N-Term

Purpose: HCRTR1 Antibody - N-terminal region

Sequence: ATPGAQMGVP PGSREPSPVP PDYEDEFLRY LWRDYLYPKQ YEWVLIAAYV

Predicted Reactivity: Cow: 85%, Dog: 91%, Guinea Pig: 83%, Human: 100%, Rabbit: 79%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HCRTR1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human HCRTR1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65327-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HCRTR1

Target: HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))

Alternative Name: HCRTR1

Background:

Background Information: The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B.

Gene Name: Hypocretin (orexin) receptor 1

Alternative Symbols: OX1R

Protein Name: Orexin receptor type 1

Molecular Weight: 47kDa

Gene ID: 3061

NCBI Accession: NP_001516

UniProt: O43613

Pathways: Feeding Behaviour