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RDH8 antibody (Retinol Dehydrogenase 8 (All-Trans)) (Middle Region) Primary Antibody

RDH8 Reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat WB Host: Rabbit Polyclonal
Catalog No. ABIN2790129
$229.00
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100 μL
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  • Target
    Binding Specificity
    Middle Region
    Reactivity
    Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
    Host
    Rabbit
    Clonality
    Polyclonal
    Application
    Western Blotting (WB)
    Blocking Peptide
    Blocking peptide for this product available: ABIN982818
    Sequence
    FDTNFFGAVR LVKAVLPGMK RRRQGHIVVI SSVMGLQGVI FNDVYAASKF
    Predicted Reactivity
    Cow: 93%, Dog: 92%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against RDH8. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of Human RDH8
  • Target
    Alternative Name
    RDH8 (RDH8 Antibody Abstract)
    Background
    All-trans-retinol dehydrogenase (RDH8) is a visual cycle enzyme that reduces all-trans-retinal to all-trans-retinol in the presence of NADPH (Rattner et al., 2000 [PubMed 10753906]). It is a member of the short chain dehydrogenase/reductase family and is located in the outer segments of photoreceptors, hence it is also known as photoreceptor retinol dehydrogenase. It is important in the visual cycle by beginning the rhodopsin regeneration pathway by reducing all-trans-retinal, the product of bleached and hydrolysed rhodopsin.
    Alias Symbols: PRRDH, SDR28C2
    Protein Size: 311
    Molecular Weight
    34 kDa
    Gene ID
    50700
    NCBI Accession
    NM_015725, NP_056540
    UniProt
    Q9NYR8
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 311 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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