SHoc2/Sur8 antibody (N-Term)

Catalog No. ABIN2790133

This Rabbit Polyclonal antibody specifically detects SHoc2/Sur8 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Horse, Dog, Rabbit, Zebrafish (Danio rerio) and Guinea Pig.

Quick Overview for SHoc2/Sur8 antibody (N-Term) (ABIN2790133)

Target: SHoc2/Sur8 (SHOC2) (Leucine-rich repeat protein SHOC-2 (SHOC2))

Reactivity: Human, Mouse, Rat, Cow, Horse, Dog, Rabbit, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHoc2/Sur8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SHoc2/Sur8 Antibody

Binding Specificity: N-Term

Sequence: NPAPGTRKKS SNAEVIKELN KCREENSMRL DLSKRSIHIL PSSIKELTQL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against SHOC2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SHOC2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SHoc2/Sur8

Target: SHoc2/Sur8 (SHOC2) (Leucine-rich repeat protein SHOC-2 (SHOC2))

Alternative Name: SHOC2

Background: This gene encodes a protein that consists almost entirely of leucine-rich repeats, a domain implicated in protein-protein interactions. The protein may function as a scaffold linking RAS to downstream signal transducers in the RAS/ERK MAP kinase signaling cascade. Mutations in this gene have been associated with Noonan-like syndrome with loose anagen hair.
Alias Symbols: SIAA0862, SOC2, SUR8
Protein Interaction Partner: MRAS, HUWE1, UBC, RAF1, ESR1, APP, Shoc2, MYC, ERBB2IP, KRAS, HRAS, NRAS,
Protein Size: 536

Molecular Weight: 58 kDa

Gene ID: 8036

NCBI Accession: NM_007373, NP_031399