SHoc2/Sur8 antibody (AA 3-89)

Catalog No. ABIN7158098

This Rabbit Polyclonal antibody specifically detects SHoc2/Sur8 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for SHoc2/Sur8 antibody (AA 3-89) (ABIN7158098)

Target: SHoc2/Sur8 (SHOC2) (Leucine-rich repeat protein SHOC-2 (SHOC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHoc2/Sur8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SHoc2/Sur8 Antibody

Binding Specificity: AA 3-89

Purpose: SHOC2 Antibody

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Leucine-rich repeat protein SHOC-2 protein (3-89AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SHoc2/Sur8

Target: SHoc2/Sur8 (SHOC2) (Leucine-rich repeat protein SHOC-2 (SHOC2))

Alternative Name: SHOC2

Background:

Background: Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the \\\'Ser-259\\\' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.

Aliases: KIAA0862 antibody, Leucine-rich repeat protein SHOC-2 antibody, Protein soc-2 homolog antibody, Protein Sur-8 homolog antibody, Ras-binding protein Sur-8 antibody, SHOC2 antibody, SHOC2_HUMAN antibody

UniProt: Q9UQ13