PHAX antibody (Middle Region)

Catalog No. ABIN2790159

This Rabbit Polyclonal antibody specifically detects PHAX in WB. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Cow, Dog and Pig.

Quick Overview for PHAX antibody (Middle Region) (ABIN2790159)

Target: PHAX (phosphorylated Adaptor For RNA Export (PHAX))

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHAX antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PHAX Antibody

Binding Specificity: Middle Region

Sequence: NYLLAKKLRK ESQEHTKDLD KELDEYMHGG KKMGSKEEEN GQGHLKRKRP

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 75%, Horse: 92%, Human: 100%, Mouse: 77%, Pig: 83%, Rabbit: 79%, Rat: 77%

Characteristics: This is a rabbit polyclonal antibody against PHAX. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human PHAX

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PHAX

Target: PHAX (phosphorylated Adaptor For RNA Export (PHAX))

Alternative Name: PHAX

Background: PHAX is a phosphoprotein adapter involved in the XPO1-mediated U snRNA export from the nucleus. PHAX is also a bridge components required for U snRNA export, the cap binding complex (CBC)-bound snRNA on the one hand and the GTPase Ran in its active GTP-bound form together with the export receptor XPO1 on the other.
Alias Symbols: RNUXA
Protein Interaction Partner: CIAO1, UBC, LIN28B, LIN28A, ZNF346, HSP90B1, CALD1, SNORD13P1, SNORD118, LOC366310, PAXIP1, EIF4B, CAND1, CUL3, SUMO2, ZWINT, GADD45G, TNFSF11, MKNK1, VAV1, STK3, RPS6KA1, RAD23A, PDPK1, GRB7, UBXN2A, ASPSCR1, NSFL1C, XPO1, SNORD3A,
Protein Size: 394

Molecular Weight: 44 kDa

Gene ID: 51808

NCBI Accession: NM_032177, NP_115553

UniProt: Q9H814

Pathways: Ribonucleoprotein Complex Subunit Organization