PTGES2 antibody (Middle Region)

Catalog No. ABIN2790225

The Rabbit Polyclonal anti-PTGES2 antibody is suitable to detect PTGES2 in samples from Human, Mouse, Rat, Dog, Guinea Pig and Horse. It has been validated for WB.

Quick Overview for PTGES2 antibody (Middle Region) (ABIN2790225)

Target: PTGES2 (Prostaglandin E Synthase 2 (PTGES2))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGES2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PTGES2 Antibody

Binding Specificity: Middle Region

Sequence: VAKYMGAAAM YLISKRLKSR HRLQDNVRED LYEAADKWVA AVGKDRPFMG

Predicted Reactivity: Dog: 86%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 79%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against PTGES2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human PTGES2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 186 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PTGES2

Target: PTGES2 (Prostaglandin E Synthase 2 (PTGES2))

Alternative Name: PTGES2

Background: The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene.
Alias Symbols: C9orf15, FLJ14038, GBF1, MGC11289, PGES2, mPGES-2, GBF-1
Protein Interaction Partner: C1orf189, SUMO2, PTGES2, HTT, UBC, UQCR11, MYC, H2AFX, EXOSC10, PTGFR, CEBPB,
Protein Size: 186

Molecular Weight: 21 kDa

Gene ID: 80142

NCBI Accession: NM_198938, NP_945176

UniProt: A6NHH0

Pathways: Interferon-gamma Pathway, Cell RedoxHomeostasis, SARS-CoV-2 Protein Interactome