GMIP antibody (C-Term)

Catalog No. ABIN2790252

This Rabbit Polyclonal antibody specifically detects GMIP in WB. It exhibits reactivity toward Human, Dog, Horse and Rabbit.

Quick Overview for GMIP antibody (C-Term) (ABIN2790252)

Target: GMIP (GEM Interacting Protein (GMIP))

Reactivity: Human, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GMIP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GMIP Antibody

Binding Specificity: C-Term

Purpose: GMIP Antibody - C-terminal region

Sequence: PGPDPQHHST LEQHPTATPT EIPTPQSDQR EDVAEDTKDG GGEVSSQGPE

Predicted Reactivity: Dog: 86%, Horse: 93%, Human: 100%, Rabbit: 85%

Characteristics: This is a rabbit polyclonal antibody against GMIP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human GMIP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65759-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GMIP

Target: GMIP (GEM Interacting Protein (GMIP))

Alternative Name: GMIP

Background:

Background Information: This gene encodes a member of the ARHGAP family of Rho/Rac/Cdc42-like GTPase activating proteins. The encoded protein interacts with the Ras-related protein Gem through its N-terminal domain. Separately, it interacts with RhoA through a RhoGAP domain, and stimulates RhoA-dependent GTPase activity. Alternatively spliced variants that encode different protein isoforms have been described but their full-length nature has not been determined.

Alternative Symbols: ARHGAP46

Protein Name: GEM-interacting protein

Molecular Weight: 107kDa

Gene ID: 51291

NCBI Accession: NP_057657

UniProt: Q9P107