Importin 8 antibody (C-Term)
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- Target See all Importin 8 (IPO8) Antibodies
- Importin 8 (IPO8)
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat, Dog, Horse, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Importin 8 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- PPAVDAVVGQ IVPSILFLFL GLKQVCATRQ LVNREDRSKA EKADMEENEE
- Predicted Reactivity
- Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against IPO8. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human IPO8
- Top Product
- Discover our top product IPO8 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 832 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Importin 8 (IPO8)
- Alternative Name
- IPO8 (IPO8 Products)
- Synonyms
- IPO8 antibody, si:ch211-116i17.1 antibody, RANBP8 antibody, 6230418K12Rik antibody, Abcc10 antibody, C130009K11Rik antibody, MRP7 antibody, OM-1 antibody, Om1 antibody, Ranbp8 antibody, importin 8 antibody, IPO8 antibody, ipo8 antibody, Ipo8 antibody
- Background
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The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FLJ26580, RANBP8
Protein Interaction Partner: UBC, EGFR, YWHAE, CBX5, ATXN1, CUL3, Trim28, AGO4, AGO3, AGO2, AGO1, KPNB1, RANGAP1, SRP19, RPL23A,
Protein Size: 832 - Molecular Weight
- 96 kDa
- Gene ID
- 10526
- NCBI Accession
- NM_001190995, NP_001177924
- UniProt
- O15397
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