LAMC3 antibody (C-Term)

Catalog No. ABIN2790263

The Rabbit Polyclonal anti-LAMC3 antibody is suitable to detect LAMC3 in samples from Human, Cow, Horse, Pig and Rabbit. It has been validated for WB.

Quick Overview for LAMC3 antibody (C-Term) (ABIN2790263)

Target: LAMC3 (Laminin, gamma 3 (LAMC3))

Reactivity: Human, Cow, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAMC3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LAMC3 Antibody

Binding Specificity: C-Term

Sequence: ERMLGNAAPL SSSAKKKGRE AEVLAKDSAK LAKALLRERK QAHRRASRLT

Predicted Reactivity: Cow: 92%, Horse: 92%, Human: 100%, Pig: 92%, Rabbit: 83%

Characteristics: This is a rabbit polyclonal antibody against LAMC3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human LAMC3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1379 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LAMC3

Target: LAMC3 (Laminin, gamma 3 (LAMC3))

Alternative Name: LAMC3

Background: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene.
Alias Symbols: RP11-143H20.1, OCCM
Protein Interaction Partner: YTHDC1, ZNF160, PELI2, CWC25, EPB41L4B, SLC43A3, POT1, RPL35, KIF1C, FRAT1, NR1H2, UBC, TF, LGMN, HP, CYP2E1, CSNK2A2, CRP, CFB, ANXA5, SERPINA3,
Protein Size: 1379

Molecular Weight: 140 kDa

Gene ID: 10319

NCBI Accession: NM_006059

UniProt: Q9Y6N6