LIMS2 antibody (N-Term)

Catalog No. ABIN2790264

The Rabbit Polyclonal anti-LIMS2 antibody (ABIN2790264) specifically detects LIMS2 in WB. The antibody is reactive with Mouse, Human, Rat, Cow, Dog, Horse, Pig, Rabbit, Goat, Guinea Pig and Zebrafish (Danio rerio) samples.

Quick Overview for LIMS2 antibody (N-Term) (ABIN2790264)

Target: LIMS2 (LIM and Senescent Cell Antigen-Like Domains 2 (LIMS2))

Reactivity: Mouse, Human, Rat, Cow, Dog, Horse, Pig, Rabbit, Goat, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIMS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LIMS2 Antibody

Binding Specificity: N-Term

Purpose: LIMS2 Antibody - N-terminal region

Sequence: DVELADLGFV KNAGRHLCRP CHNREKAKGL GKYICQRCHL VIDEQPLMFR

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against LIMS2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human LIMS2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65780-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for LIMS2

Target: LIMS2 (LIM and Senescent Cell Antigen-Like Domains 2 (LIMS2))

Alternative Name: LIMS2

Background:

Background Information: This gene encodes a member of a small family of focal adhesion proteins which interacts with ILK (integrin-linked kinase), a protein which effects protein-protein interactions with the extraceullar matrix. The encoded protein has five LIM domains, each domain forming two zinc fingers, which permit interactions which regulate cell shape and migration. A pseudogene of this gene is located on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative Symbols: LGMD2W, PINCH2, MDRCMTT, PINCH-2

Protein Name: LIM and senescent cell antigen-like-containing domain protein 2

Molecular Weight: 38kDa

Gene ID: 55679

NCBI Accession: NP_001154876

UniProt: Q7Z4I7

Pathways: Cell-Cell Junction Organization