Otopetrin 1 antibody (C-Term)

Catalog No. ABIN2790271

The Rabbit Polyclonal anti-Otopetrin 1 antibody is suitable to detect Otopetrin 1 in samples from Mouse, Human, Rat, Guinea Pig, Horse, Cow, Dog and Rabbit. It has been validated for WB.

Quick Overview for Otopetrin 1 antibody (C-Term) (ABIN2790271)

Target: Otopetrin 1 (OTOP1)

Reactivity: Mouse, Human, Rat, Guinea Pig, Horse, Cow, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Otopetrin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Otopetrin 1 Antibody

Binding Specificity: C-Term

Purpose: OTOP1 Antibody - C-terminal region

Sequence: KTKSESALIM FYLYAITLLM LMGAAGLAGI RIYRIDEKSL DESKNPARKL

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against OTOP1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human OTOP1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65798-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Otopetrin 1

Target: Otopetrin 1 (OTOP1)

Alternative Name: OTOP1

Background:

Background Information: OTOP1 is required for normal formation of otoconia in the inner ear. OTOP1 inhibits P2Y purinoceptors and modulates calcium homeostasis and influx of calcium in response to extracellular ATP.

Gene Name: Otopetrin 1

Alternative Symbols: MGC163302, MGC163304

Protein Name: Otopetrin-1

Molecular Weight: 67kDa

Gene ID: 133060

NCBI Accession: NP_819056

UniProt: Q7RTM1