PPP1CB antibody (C-Term)

Catalog No. ABIN2790274

This Rabbit Polyclonal antibody specifically detects PPP1CB in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig and Saccharomyces cerevisiae.

Quick Overview for PPP1CB antibody (C-Term) (ABIN2790274)

Target: PPP1CB (Protein Phosphatase 1, Catalytic Subunit, beta Isoform (PPP1CB))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1CB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PPP1CB Antibody

Binding Specificity: C-Term

Sequence: LFSAPNYCGE FDNAGGMMSV DETLMCSFQI LKPSEKKAKY QYGGLNSGRP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PPP1CB. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PPP1CB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 327 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPP1CB

Target: PPP1CB (Protein Phosphatase 1, Catalytic Subunit, beta Isoform (PPP1CB))

Alternative Name: PPP1CB

Background: The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alias Symbols: MGC3672, PP-1B, PP1beta, PPP1CD
Protein Interaction Partner: PPP1R3C, PPP1R2P3, PPP1R16A, CSRNP2, SH2D4A, UBC, TP53BP2, SUMO2, SUMO3, NUAK1, EED, DENR, MVK, EEF1A1, DHX15, PAN2, RHO, ZFYVE9, MDM4, KAT8, WDR5, PAPOLA, OGT, AURKA, PPP1CA, HCFC1, CUL3, PTK2, MAX, LBR, HSPA4, CDKN2A, CDC34, CCND3, CCNB1, BCL2, CCND1, S
Protein Size: 327

Molecular Weight: 37 kDa

Gene ID: 5500

NCBI Accession: NM_002709, NP_002700

UniProt: P62140

Pathways: M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism