Variable Charge, Y-Linked (VCY) (N-Term) antibody

Catalog No. ABIN2790281

Product Details

Target: Variable Charge, Y-Linked (VCY)

Binding Specificity: N-Term

Reactivity: Human, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Sequence: PPAKAKETGK RKSSSQPSPS GPKKKTTKVA EKGEAVRGGR RGKKGAATKM

Predicted Reactivity: Horse: 93%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against VCY. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human VCY

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 125 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: Variable Charge, Y-Linked (VCY)

Alternative Name: VCY (VCY Products)

Synonyms: BPY1 antibody, VCY1 antibody, VCY1A antibody, variable charge, Y-linked antibody, VCY antibody

Background: The protein encoded by this gene is a member of a family of human VCX/Y genes. This gene family has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. Members of the VCX/Y family share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. VCX/Y genes encode small and highly charged proteins of unknown function. This gene encodes a small, positively charged protein. The presence of a putative bipartite nuclear localization signal suggests that this gene encodes a nuclear protein. The genome has two identical copies of this gene within a palindromic region, this record represents the more centromeric copy.
Alias Symbols: BPY1, MGC119817, VCY1, VCY1A, VCY1B
Protein Size: 125

Molecular Weight: 13 kDa

Gene ID: 9084

NCBI Accession: NM_004679, NP_004670

UniProt: O14598