Variable Charge, Y-Linked (VCY) (N-Term) antibody

Catalog No. ABIN2790281

The Rabbit Polyclonal anti-Variable Charge, Y-Linked antibody is suitable to detect Variable Charge, Y-Linked in samples from Human and Horse. It has been validated for WB.

Quick Overview for Variable Charge, Y-Linked (VCY) (N-Term) antibody (ABIN2790281)

Target: Variable Charge, Y-Linked (VCY)

Reactivity: Human, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: N-Term

Purpose: VCY Antibody - N-terminal region

Sequence: PPAKAKETGK RKSSSQPSPS GPKKKTTKVA EKGEAVRGGR RGKKGAATKM

Predicted Reactivity: Horse: 93%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against VCY. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human VCY

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65848-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: Variable Charge, Y-Linked (VCY)

Alternative Name: VCY

Background:

Background Information: The protein encoded by this gene is a member of a family of human VCX/Y genes. This gene family has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. Members of the VCX/Y family share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. VCX/Y genes encode small and highly charged proteins of unknown function. This gene encodes a small, positively charged protein. The presence of a putative bipartite nuclear localization signal suggests that this gene encodes a nuclear protein. The genome has two identical copies of this gene within a palindromic region, this record represents the more centromeric copy.

Gene Name: Variable charge, Y-linked

Alternative Symbols: BPY1, VCY1, VCY1A

Protein Name: Testis-specific basic protein Y 1

Molecular Weight: 13kDa

Gene ID: 9084

NCBI Accession: NP_004670

UniProt: O14598