Der1-Like Domain Family, Member 2 (DERL2) (C-Term) antibody

Catalog No. ABIN2790288

Product Details

Target: Der1-Like Domain Family, Member 2 (DERL2)

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Sequence: DVFPNQPGGI RILKTPSILK AIFDTPDEDP NYNPLPEERP GGFAWGEGQR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against DERL2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DERL2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 235 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: Der1-Like Domain Family, Member 2 (DERL2)

Alternative Name: DERL2 (DERL2 Products)

Synonyms: F-LAN-1 antibody, F-LANa antibody, FLANa antibody, BC005682 antibody, CGI-101 antibody, Derlin-2 antibody, F-lana antibody, Flana antibody, RP23-83I13.8 antibody, derl2 antibody, zgc:110436 antibody, CG14899 antibody, Cg14899 antibody, DER1 antibody, Dmel\\CG14899 antibody, derlin 2 antibody, Der1-like domain family, member 2 antibody, derlin-2 antibody, derlin-2.1 antibody, derlin 2 S homeolog antibody, Derlin-2 antibody, DERL2 antibody, Derl2 antibody, derl2 antibody, PVX_117040 antibody, CpipJ_CPIJ012528 antibody, MCYG_03163 antibody, VDBG_06959 antibody, LOAG_05811 antibody, MGYG_00329 antibody, derl2.S antibody, Der-2 antibody

Background: Proteins that are unfolded or misfolded in the endoplasmic reticulum (ER) must be refolded or degraded to maintain the homeostasis of the ER. DERL2 is involved in the degradation of misfolded glycoproteins in the ER.
Alias Symbols: CGI-101, F-LAN-1, F-LANa, FLANa
Protein Interaction Partner: KRTAP10-3, KRTAP10-8, KRTAP10-7, SYVN1, HEY2, HEY1, SEL1L, OS9, HERPUD1, VCP, SHH, SERPINA1, AMFR, DERL1, VIMP, SARAF, UBC, Dlg4, EDEM1, CUL2, FAF2, BAG6, UBE2J1, MFI2,
Protein Size: 235

Molecular Weight: 27 kDa

Gene ID: 51009

NCBI Accession: NM_016041, NP_057125

UniProt: Q96Q80

Pathways: ER-Nucleus Signaling, Feeding Behaviour