Der1-Like Domain Family, Member 2 (DERL2) (C-Term) antibody

Catalog No. ABIN2790288

The Rabbit Polyclonal anti-Der1-Like Domain Family, Member 2 antibody is suitable to detect Der1-Like Domain Family, Member 2 in samples from Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Dog, Horse and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for Der1-Like Domain Family, Member 2 (DERL2) (C-Term) antibody (ABIN2790288)

Target: Der1-Like Domain Family, Member 2 (DERL2)

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Dog, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: C-Term

Purpose: DERL2 Antibody - C-terminal region

Sequence: DVFPNQPGGI RILKTPSILK AIFDTPDEDP NYNPLPEERP GGFAWGEGQR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against DERL2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DERL2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65880-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: Der1-Like Domain Family, Member 2 (DERL2)

Alternative Name: DERL2

Background:

Background Information: Proteins that are unfolded or misfolded in the endoplasmic reticulum (ER) must be refolded or degraded to maintain the homeostasis of the ER. DERL2 is involved in the degradation of misfolded glycoproteins in the ER.

Alternative Symbols: FLANa, F-LANa, CGI-101, F-LAN-1, derlin-2, DERtrin-2

Protein Name: Derlin-3

Molecular Weight: 27kDa

Gene ID: 51009

NCBI Accession: NP_057125

UniProt: Q96Q80

Pathways: ER-Nucleus Signaling, Feeding Behaviour