Heparanase 2 antibody (N-Term)

Catalog No. ABIN2790293

This Rabbit Polyclonal antibody specifically detects Heparanase 2 in WB. It exhibits reactivity toward Human, Mouse and Dog.

Quick Overview for Heparanase 2 antibody (N-Term) (ABIN2790293)

Target: Heparanase 2 (HPSE2)

Reactivity: Human, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Heparanase 2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Heparanase 2 Antibody

Binding Specificity: N-Term

Purpose: HPSE2 Antibody - N-terminal region

Sequence: SPAFLRFGGK RTDFLQFQNL RNPAKSRGGP GPDYYLKNYE DEPNNYRTMH

Predicted Reactivity: Dog: 100%, Human: 100%, Mouse: 100%

Characteristics: This is a rabbit polyclonal antibody against HPSE2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human HPSE2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65898-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Heparanase 2

Target: Heparanase 2 (HPSE2)

Alternative Name: HPSE2

Background:

Background Information: This gene encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants.

Alternative Symbols: UFS, HPA2, HPR2, UFS1

Protein Name: Inactive heparanase-2

Molecular Weight: 54kDa

Gene ID: 60495

NCBI Accession: NP_001159717

UniProt: Q8WWQ2

Pathways: Glycosaminoglycan Metabolic Process