STAG2 antibody (C-Term)

Catalog No. ABIN2790312

The Rabbit Polyclonal anti-STAG2 antibody (ABIN2790312) specifically detects STAG2 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Pig and Rabbit samples.

Quick Overview for STAG2 antibody (C-Term) (ABIN2790312)

Target: STAG2 (Stromal Antigen 2 (STAG2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAG2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-STAG2 Antibody

Binding Specificity: C-Term

Purpose: STAG2 Antibody - C-terminal region

Sequence: LLAGGDDDTM SVISGISSRG STVRSKKSKP STGKRKVVEG MQLSLTEESS

Predicted Reactivity: Cow: 100%, Dog: 100%, Human 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against STAG2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human STAG2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65973-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for STAG2

Target: STAG2 (Stromal Antigen 2 (STAG2))

Alternative Name: STAG2

Background:

Targeted Subunit: SA-2

Background Information: STAG2 is a component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.

Alternative Symbols: SA2, MKMS, SA-2, HPE13, SCC3B, NEDXCF, bA517O1.1

Protein Name: Cohesin subunit SA-2

Molecular Weight: 141kDa

Gene ID: 10735

NCBI Accession: NP_006594

UniProt: Q8N3U4

Pathways: Stem Cell Maintenance