CHRDL2 antibody (N-Term)

Catalog No. ABIN2790324

The Rabbit Polyclonal anti-CHRDL2 antibody is suitable to detect CHRDL2 in samples from Human, Mouse, Rat and Saccharomyces cerevisiae. It has been validated for WB.

Quick Overview for CHRDL2 antibody (N-Term) (ABIN2790324)

Target: CHRDL2 (Chordin-Like 2 (CHRDL2))

Reactivity: Human, Mouse, Rat, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRDL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHRDL2 Antibody

Binding Specificity: N-Term

Purpose: CHRDL2 Antibody - N-terminal region

Sequence: CTEGQIYCGL TTCPEPGCPA PLPLPDSCCQ ACKDEASEQS DEEDSVQSLH

Predicted Reactivity: Human: 100%, Mouse: 83%, Rat: 75%, Yeast: 90%

Characteristics: This is a rabbit polyclonal antibody against CHRDL2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CHRDL2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP66005-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHRDL2

Target: CHRDL2 (Chordin-Like 2 (CHRDL2))

Alternative Name: CHRDL2

Background:

Background Information: CHRDL2 is implicated in tumor angiogenesis. CHRDL2 may inhibits BMPs activity by blocking their interaction with their receptors. CHRDL2 has a negative regulator effect on the cartilage formation/regeneration from immature mesenchymal cells, by preventing or reducing the rate of matrix accumulation. CHRDL2 may play a role during myoblast and osteoblast differentiation, and maturation.

Alternative Symbols: BNF1, CHL2

Protein Name: Chordin-like protein 2

Molecular Weight: 3kDa

Gene ID: 25884

NCBI Accession: NP_056239

UniProt: Q6WN34