CHRDL2 antibody (N-Term)

Catalog No. ABIN2790324

Product Details anti-CHRDL2 Antibody

Target: CHRDL2 (Chordin-Like 2 (CHRDL2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRDL2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: CTEGQIYCGL TTCPEPGCPA PLPLPDSCCQ ACKDEASEQS DEEDSVQSLH

Predicted Reactivity: Human: 100%, Mouse: 83%, Rat: 75%, Yeast: 90%

Characteristics: This is a rabbit polyclonal antibody against CHRDL2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CHRDL2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 451 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHRDL2

Target: CHRDL2 (Chordin-Like 2 (CHRDL2))

Alternative Name: CHRDL2 (CHRDL2 Products)

Synonyms: BNF1 antibody, CHL2 antibody, FKSG37 antibody, 1810022C01Rik antibody, Chl2 antibody, chl antibody, si:dkey-11j5.7 antibody, si:dkey-11j5.7-like antibody, chordin like 2 antibody, chordin-like 2 antibody, CHRDL2 antibody, Chrdl2 antibody, chrdl2 antibody

Background: CHRDL2 is implicated in tumor angiogenesis. CHRDL2 may inhibits BMPs activity by blocking their interaction with their receptors. CHRDL2 has a negative regulator effect on the cartilage formation/regeneration from immature mesenchymal cells, by preventing or reducing the rate of matrix accumulation. CHRDL2 may play a role during myoblast and osteoblast differentiation, and maturation.
Alias Symbols: BNF1, CHL2, DKFZp586N2124, FKSG37
Protein Interaction Partner: GDF5, INHBA, BMP7, BMP6, BMP5, BMP4, BMP2,
Protein Size: 451

Molecular Weight: 3 kDa

Gene ID: 25884

NCBI Accession: NM_015424, NP_056239

UniProt: Q6WN34