DGKD antibody (C-Term)

Catalog No. ABIN2790326

This Rabbit Polyclonal antibody specifically detects DGKD in WB. It exhibits reactivity toward Human, Mouse, Dog, Guinea Pig, Rabbit and Rat.

Quick Overview for DGKD antibody (C-Term) (ABIN2790326)

Target: DGKD (Diacylglycerol Kinase, delta 130kDa (DGKD))

Reactivity: Human, Mouse, Dog, Guinea Pig, Rabbit, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DGKD antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DGKD Antibody

Binding Specificity: C-Term

Sequence: KRSRSGKFRL VTKFKKEKNN KNKEAHSSLG APVHLWGTEE VAAWLEHLSL

Predicted Reactivity: Dog: 79%, Guinea Pig: 93%, Human: 100%, Mouse: 92%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DGKD. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DGKD

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1170 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DGKD

Target: DGKD (Diacylglycerol Kinase, delta 130kDa (DGKD))

Alternative Name: DGKD

Background: This gene encodes a cytoplasmic enzyme that phosphorylates diacylglycerol to produce phosphatidic acid. Diacylglycerol and phosphatidic acid are two lipids that act as second messengers in signaling cascades. Their cellular concentrations are regulated by the encoded protein, and so it is thought to play an important role in cellular signal transduction. Alternative splicing results in two transcript variants encoding different isoforms.
Alias Symbols: DGKdelta, FLJ26930, KIAA0145, dgkd-2
Protein Interaction Partner: UBC, SREK1, TNFRSF14, HAX1, IGSF21, DGKH, DGKD, PRKCA, MYH2,
Protein Size: 1170

Molecular Weight: 130 kDa

Gene ID: 8527

NCBI Accession: NM_003648, NP_003639

UniProt: Q16760

Pathways: EGFR Signaling Pathway