DGKD antibody (C-Term)

Catalog No. ABIN2790326

This Rabbit Polyclonal antibody specifically detects DGKD in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig and Rabbit.

Quick Overview for DGKD antibody (C-Term) (ABIN2790326)

Target: DGKD (Diacylglycerol Kinase, delta 130kDa (DGKD))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DGKD antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DGKD Antibody

Binding Specificity: C-Term

Purpose: DGKD Antibody - C-terminal region

Sequence: KRSRSGKFRL VTKFKKEKNN KNKEAHSSLG APVHLWGTEE VAAWLEHLSL

Predicted Reactivity: Dog: 79%, Guinea Pig: 93%, Human: 100%, Mouse: 92%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DGKD. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DGKD

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP66016-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DGKD

Target: DGKD (Diacylglycerol Kinase, delta 130kDa (DGKD))

Alternative Name: DGKD

Background:

Background Information: This gene encodes a cytoplasmic enzyme that phosphorylates diacylglycerol to produce phosphatidic acid. Diacylglycerol and phosphatidic acid are two lipids that act as second messengers in signaling cascades. Their cellular concentrations are regulated by the encoded protein, and so it is thought to play an important role in cellular signal transduction. Alternative splicing results in two transcript variants encoding different isoforms.

Alternative Symbols: dgkd-2, DGKdelta, DGK-delta

Protein Name: Diacylglycerol kinase delta

Molecular Weight: 130kDa

Gene ID: 8527

NCBI Accession: NP_003639

UniProt: Q16760

Pathways: EGFR Signaling Pathway