Calpain 8 antibody (Middle Region)

Catalog No. ABIN2790353

The Rabbit Polyclonal anti-Calpain 8 antibody is suitable to detect Calpain 8 in samples from Human, Rat, Guinea Pig, Horse and Rabbit. It has been validated for WB.

Quick Overview for Calpain 8 antibody (Middle Region) (ABIN2790353)

Target: Calpain 8 (CAPN8)

Reactivity: Human, Rat, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calpain 8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Calpain 8 Antibody

Binding Specificity: Middle Region

Purpose: CAPN8 Antibody - middle region

Sequence: KLIRLRNPWG EVEWSGAWSD DAPEWNHIDP RRKEELDKKV EDGEFWMSLS

Predicted Reactivity: Guinea Pig: 79%, Horse: 79%, Human: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CAPN8. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human CAPN8

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP66137-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Calpain 8

Target: Calpain 8 (CAPN8)

Alternative Name: CAPN8

Background:

Background Information: CAPN8 is a calcium-regulated non-lysosomal thiol-protease. CAPN8 is involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. CAPN8 proteolytically cleaves the beta-subunit of coatomer complex.

Alternative Symbols: nCL-2

Protein Name: Calpain-8

Molecular Weight: 77kDa

Gene ID: 388743

NCBI Accession: NP_001137434

UniProt: A6NHC0