FYCO1 antibody (N-Term)

Catalog No. ABIN2790358

Product Details anti-FYCO1 Antibody

Target: FYCO1 (FYVE and Coiled-Coil Domain Containing 1 (FYCO1))

Binding Specificity: N-Term

Reactivity: Human, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FYCO1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PLAQELEATR DSLDKKNQHL ASFPGWLAMA QQKADTASDT KGRQEPIPSD

Predicted Reactivity: Horse: 86%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against FYCO1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human FYCO1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1478 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FYCO1

Target: FYCO1 (FYVE and Coiled-Coil Domain Containing 1 (FYCO1))

Alternative Name: FYCO1 (FYCO1 Products)

Background: This gene encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2).
Alias Symbols: DKFZp779K1152, FLJ13335, MGC126517, MGC126519, RUFY3, ZFYVE7
Protein Interaction Partner: RAF1, UBC, PRMT6, KDM1A, MAP1LC3A, IQCB1, APP, MAP1LC3B, SEC24B, KIF23, TMPO, RPA3, RPA2, RPA1, MAP4, LMNA, KIF5B, EMD, FOXK1, CCAR1, CCZ1, C18orf8, MON1B, SEC23B,
Protein Size: 1478

Molecular Weight: 167 kDa

Gene ID: 79443

NCBI Accession: NM_024513, NP_078789

UniProt: Q9BQS8

Pathways: SARS-CoV-2 Protein Interactome