FYCO1 antibody

Catalog No. ABIN7228604

The Rabbit Polyclonal anti-FYCO1 antibody (ABIN7228604) specifically detects FYCO1 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for FYCO1 antibody (ABIN7228604)

Target: FYCO1 (FYVE and Coiled-Coil Domain Containing 1 (FYCO1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FYCO1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FYCO1 Antibody

Purpose: Rabbit Anti-FYCO1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of FYCO1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human FYCO1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FYCO1

Target: FYCO1 (FYVE and Coiled-Coil Domain Containing 1 (FYCO1))

Alternative Name: FYCO1

Background: FYVE and coiled-coil domain-containing protein 1, Zinc finger FYVE domain-containing protein 7FYCO1 encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in FYCO1 are a cause of autosomal recessive congenital cataract-2 (CATC2). FYCO1 (FYVE And Coiled-Coil Domain Containing 1) is a Protein Coding gene. Diseases associated with FYCO1 include Cataract 18, Autosomal Recessive and Early-Onset Nuclear Cataract.

Molecular Weight: 162kD

Gene ID: 79443

UniProt: Q9BQS8

Pathways: SARS-CoV-2 Protein Interactome