CNOT6L antibody (Middle Region)

Catalog No. ABIN2790464

Product Details anti-CNOT6L Antibody

Target: CNOT6L (CCR4-NOT Transcription Complex, Subunit 6-Like (CNOT6L))

Binding Specificity: Middle Region

Reactivity: Human, Horse, Mouse, Cow, Rabbit, Dog, Rat, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNOT6L antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AKIMSEQERK HVDGCAIFFK TEKFTLVQKH TVEFNQVAMA NSDGSEAMLN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against CNOT6L. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human CNOT6L

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CNOT6L

Target: CNOT6L (CCR4-NOT Transcription Complex, Subunit 6-Like (CNOT6L))

Alternative Name: CNOT6L (CNOT6L Products)

Synonyms: 4932442K20Rik antibody, CCR4b antibody, ccr4b antibody, zgc:111987 antibody, cnot6l antibody, cnot6l-a antibody, cnot6l-b antibody, CCR4-NOT transcription complex, subunit 6-like antibody, CCR4-NOT transcription complex subunit 6 like antibody, CCR4-NOT transcription complex subunit 6-like L homeolog antibody, CCR4-NOT transcription complex subunit 6 antibody, CCR4-NOT transcription complex subunit 6-like S homeolog antibody, Cnot6l antibody, CNOT6L antibody, cnot6l.L antibody, cnot6l antibody, CNOT6 antibody, cnot6l.S antibody

Background: CNOT6L plays a role in the deadenylation of mRNAs in the cytoplasm. Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. It may be involved in the deadenylation-dependent degradation of mRNAs through the 3'-UTR AU-rich element-mediated mechanism. Involved in deadenylation-dependent degradation of CDKN1B mRNA.
Protein Interaction Partner: TNKS1BP1, CNOT10, CNOT1, CHAF1A, RQCD1, CHAF1B, CNOT3, CNOT2, ZSCAN1, LZTR1, BTG2,
Protein Size: 475

Molecular Weight: 52 kDa

Gene ID: 246175