COX7A2 antibody (Middle Region)

Catalog No. ABIN2790466

This Rabbit Polyclonal antibody specifically detects COX7A2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog, Sheep and Zebrafish (Danio rerio).

Quick Overview for COX7A2 antibody (Middle Region) (ABIN2790466)

Target: COX7A2 (Cytochrome C Oxidase Subunit VIIa Polypeptide 2 (Liver) (COX7A2))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX7A2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-COX7A2 Antibody

Binding Specificity: Middle Region

Purpose: COX7A2 Antibody - middle region

Sequence: ASRRHFKNKV PEKQKLFQED DEIPLYLKGG VADALLYRAT MILTVGGTAY

Predicted Reactivity: Cow: 85%, Dog: 85%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 77%, Rabbit: 85%, Rat: 77%, Sheep: 85%, Zebrafish: 75%

Characteristics: This is a rabbit polyclonal antibody against COX7A2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human COX7A2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP66547-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for COX7A2

Target: COX7A2 (Cytochrome C Oxidase Subunit VIIa Polypeptide 2 (Liver) (COX7A2))

Alternative Name: COX7A2

Background:

Background Information: Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues.

Gene Name: cytochrome c oxidase subunit VIIa polypeptide 2 (liver)

Alternative Symbols: VIIAL, COX7AL, COX7AL1, COXVIIAL, COXVIIa-L

Protein Name: Cytochrome c oxidase subunit 7A2, mitochondrial Ensembl ENSP00000359106 Ensembl ENSP00000359098

Molecular Weight: 12kDa

Gene ID: 1347

NCBI Accession: NP_001856

UniProt: H0UI06