NKAP antibody (C-Term)

Catalog No. ABIN2790485

The Rabbit Polyclonal anti-NKAP antibody has been validated for WB. It is suitable to detect NKAP in samples from Human, Rat, Mouse, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig, Saccharomyces cerevisiae and Zebrafish (Danio rerio).

Quick Overview for NKAP antibody (C-Term) (ABIN2790485)

Target: NKAP (NFKB Activating Protein (NKAP))

Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKAP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NKAP Antibody

Binding Specificity: C-Term

Sequence: EAVRLRKENQ IYSADEKRAL ASFNQEERRK RENKILASFR EMVYRKTKGK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against NKAP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human NKAP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 415 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NKAP

Target: NKAP (NFKB Activating Protein (NKAP))

Alternative Name: NKAP

Background: This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6.
Alias Symbols: FLJ22626
Protein Interaction Partner: UBC, SRPK1, CSNK2A2, TTC14, FRA10AC1, NKAP, PRPF40A, RBMX2, DDX41, RBM39, PPIG, BUB3, PRPF3, U2AF1, PCBP2, DHX15, DHX8, CUL5, SUMO2, LUC7L2, CEP70, THAP1, FAM124A,
Protein Size: 415

Molecular Weight: 46 kDa

Gene ID: 79576

NCBI Accession: NM_024528, NP_078804

UniProt: Q8N5F7

Pathways: Stem Cell Maintenance, The Global Phosphorylation Landscape of SARS-CoV-2 Infection