NKAP antibody (AA 10-90)

Catalog No. ABIN7230010

The Rabbit Polyclonal anti-NKAP antibody is suitable to detect NKAP in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for NKAP antibody (AA 10-90) (ABIN7230010)

Target: NKAP (NFKB Activating Protein (NKAP))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKAP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NKAP Antibody

Binding Specificity: AA 10-90

Purpose: Rabbit Anti-NKAP Polyclonal Antibody

Specificity: The antibody detects endogenous levels of NKAP protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human NKAP protein at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NKAP

Target: NKAP (NFKB Activating Protein (NKAP))

Alternative Name: NKAP

Background: NF-kappa-B-activating proteinNKAP encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6.

Molecular Weight: 45kD

Gene ID: 79576

UniProt: Q8N5F7

Pathways: Stem Cell Maintenance, The Global Phosphorylation Landscape of SARS-CoV-2 Infection