PIP5K1B antibody (C-Term)

Catalog No. ABIN2790492

The Rabbit Polyclonal anti-PIP5K1B antibody (ABIN2790492) specifically detects PIP5K1B in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse, Pig and Rabbit samples.

Quick Overview for PIP5K1B antibody (C-Term) (ABIN2790492)

Target: PIP5K1B (Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, beta (PIP5K1B))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIP5K1B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PIP5K1B Antibody

Binding Specificity: C-Term

Sequence: VFKKIQALKA SPSKKRCNSI AALKATSQEI VSSISQEWKD EKRDLLTEGQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PIP5K1B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PIP5K1B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 540 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PIP5K1B

Target: PIP5K1B (Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, beta (PIP5K1B))

Alternative Name: PIP5K1B

Background: PIP5K1B participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. It mediates RAC1-dependent reorganization of actin filaments and contributes to the activation of PLD2. Together with PIP5K1A is required after stimulation of G-protein coupled receptors for stable platelet adhesion.
Alias Symbols: MSS4, STM7
Protein Interaction Partner: UBC, PIP5KL1, BTK, SPOP,
Protein Size: 540

Molecular Weight: 61 kDa

Gene ID: 8395

NCBI Accession: NM_003558, NP_003549

UniProt: O14986

Pathways: PI3K-Akt Signaling, Inositol Metabolic Process, Cell-Cell Junction Organization